For me, it would definitely be Selestia! Though I've definitely jumped on the Milltina bandwagon, her body is chef kiss, but I still think (in terms of armature, especially for the time that Selestia came out) that Selestia still is in my #1 spot with making models. Manuka has an adorable face (and I will accept the argument that it can be better than Selestia's because of more shapekeys), but imo her body is HORRIBLE, it just feels weird to use, her shapekey proportions are just weird, and oh goodness her ARMS LENGTH, THEY'RE SO SHORT ON DEFAULT, yeah you can fix it in blender, but not everyone is great at doing blender or unity, so they have to deal with her stubby little arms. I definitely don't think she's as better as Selestia, which makes me a little upset sometimes that she has more assets than Selestia (though it's super easy to fit their clothing [except the breast part because Manuka's breasts are so weird, but she's obviously made to be more like a "loli" as much as I hate saying that lol] by scaling it to 1.030 in blender). I'm definitely a Selestia over Manuka type of model maker, and I will die with that to my grave LOL. Other than that, I think Shinano is a very well made model, and as I mentioned before I believe Milltina is as well. I've been enjoying my time working on her, the things you can do with her physics is SO nice, that I honestly, slightly, thought her body was perhaps slightly better than Selestia's. I've also been working on Uruki recently, she's super cute, I still haven't worked on her enough to get a good opinion on the base, and she is VERY new after all!
tl;dr: Selestia 4ever, better than Manuka for sure. Milltina is awesome. Selestia and Milltina lover yayay